Povidone iodine is a steady synthetic complex, which is a mix of polyvinylpyrrolidone (povidone, PVP) and natural iodine. It is otherwise called iodopovidone and PVP-I. Povidone iodine is a wide range microbicide that dispenses with microbial protein and DNA. Furthermore, it has incredible execution properties, for example, improved antimicrobial activity on a wide scope of microorganisms. Povidone iodine is utilized as a sterile drug, which is widely utilized in topical applications to fix and treat skin contaminations and minor injuries. As indicated by the U.S. Pharmacopeia, povidone iodine is a complex of iodine with povidone.
It contains not less than 9.0% and not more than 12.0% of available iodine (I), calculated on the dried basis. In 1955, povidone iodine was discovered in Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. Tests were carried out to validate the antibacterial activity of the complex. The chemical was found to be less toxic than a tincture of iodine.
Povidone iodine is employed in a wide range of applications such as skin sterilization, infection prevention, instrument sterilization, and others (including breeding and aquaculture). Skin sterilization is a major segment of the global povidone iodine market. Povidone iodine is used extensively in skin sterilization products such as povidone iodine surgical scrubs, povidone iodine solution, swab sticks used for preparation of the skin prior to surgery, and post-operative skin cleansing. It is also used in the treatment of infections in wounds; cuts; burns; ulcers such as decubitus ulcers and stasis ulcers; and diabetic wounds.
In terms of volume and value, the skin sterilization segment held major share of more than 45% of the global market in 2017. Skin sterilization is a rapidly expanding segment of the market. It is driven by the rise in demand for povidone iodine in applications such as disinfectants and antiseptics. Furthermore, increase in geriatric population is projected to augment the demand for antiseptics and disinfectants. Povidone iodine is used in a broad range of applications in veterinary medicines, primarily as antiseptic for large and small animals. Rise in inclination toward protein-rich diet is anticipated to propel the animal health care industry. Growth in disposable income allows consumers to spend on a variety of meats. This, in turn, is augmenting the demand for antiseptics.