The researchers from the Johns Hopkins Medicine claimed to have set of chemicals imbalances in brains of people. These chemical imbalances have relation to chemical glutamate and especially with schizophrenia. Additionally, they searched a method to tweak the level using a broccoli-based compound.
Supplementing broccoli sprout extract – a rich source of sulforaphane – may provide a way to lower the schizophrenia symptoms. Additionally, this may lead to reducing the unwanted side effects of medicines.
This study proves sulforaphane to be a safe supplement to prescribe people who are a high risk of schizophrenia. Akira Sawa, a professor at Johns Hopkins University School of Medicine said the study paves a way for other studies.
What is Schizophrenia?
The symptoms including hallucinations, feeling, delusions and disordered thinking, behavior, speaking, and perception indicates schizophrenia.
Drugs in the treatment of schizophrenia are not completely effective to everyone. Thus, they lead to numerous side effects such as involuntary movements, cardiovascular risk, restlessness, and stiffness.
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The study published in the journal JAMA Psychiatry is based on reducing the side effects of the schizophrenia treatments. The researchers used a magnet to measure and compare regions between the brains of the people at risk of schizophrenia. They analyzed based on the 7-Tesla magnetic resonance spectroscopy (MRS).
They found lowered levels of brain chemical glutamate by 4% in the brain of psychosis people than healthy people.
Glutamate has a key role in sending messages between brain cells. Additionally, it has a link between depression and schizophrenia. Thus, these results proved that glutamate levels play a key role in schizophrenia. In addition, while conducting tests, the rat brain responded positively to change in sulforaphane level.