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Micro Device to Study Blood Cells Opens Avenues for Organ on Chip

A new found device which is of a grain’s size makes it feasible to study cells and tiny particles in the human body. The new micro device helps in experimenting tailored in the areas of drug development and disease research using ‘Organ on Chip’ system. It also helps in testing water contamination and medical examination during natural disasters.

Its benefits such as low cost, portability, and easy usage makes it a viable tool that anyone can use.

Microchip and Its Working Process

Generally, micro fluid chip are used for blood and fluid analysis. It is passes through a transparent chip that is similar to size of a postage stamp. However, the new device goes one step further by using a three dimensional cavity in sync with chip. Here, a narrow tunnel emerges into a domed vault, creating a mini vortex that makes it easier to observe tiny particles.

According to RMIT Engineer, Dr. Kashyash Koshmanesh, to create such a cavity, the researches attach liquid metal on to a silicon mold. Later, they remove the liquid metal and leave the cavity that finds use as mini centrifuge. When the fluid sample is put into the spherical shaped cavity, it swirls inside the cavity by creating a natural vortex. Through this method it is easier to observe and study them without any need for labelling them.

The micro device needs very little fluid sample which is just 1 ml of either blood or water. It has the capacity to study tiniest particles measuring even 1 micron. However, human cells can even measure up to 15 microns.

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